Evolence… A New Type of Collagen

The field of cosmetic injectables continues to get more complicated as the newest filler, Evolence, is set to make its widespread debut in the United States.

Evolence is a type of injectable collagen made from pig tissue. It’s FDA approved as of July 2008 for the improvement of nasolabial folds, or the deep wrinkles that extend between the nose to the corners of the mouth. It’s not recommended for the lips. The results appear to last six months or more according to most articles. The big selling point is the reported lack of bruising or swelling which accompanies its injection.

I don’t have experience with this product yet, but have been invited to become trained in it. The cosmetic market is full of so many fillers nowadays, some I use (Restylane, Perlane, Juvederm, Sculptra) and some I don’t (Artefill, Radiesse, Captique, Hylaform). Time will tell if this one is all it’s hyped to be.

My problem with ALL of these fillers is the cost per syringe. The average person has a hard time spending $500-$1000 per treatment, especially in this terrible economy. If a company could market a filler that lasts a year but costs only $100 per syringe all the other ones would go out of business. I’d buy that one!

Thanks for reading.

Michigan-based Plastic Surgeon

Anthony Youn, M.D.

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Posted in: Plastic Surgery News


  1. Hi Dr. Youn-

    Curious as to why you don’t use Radiesse?

    Also, some people I know have had much less bruising/swelling/discomfort from injectable fillers for having it done intraorally; if/when I have fillers one I will be seeking a well-experienced doc who goes this route.

    (Transoral injection of Restylane SubQ for aesthetic contouring of the cheeks . Aesthetic Surgery Journal , Volume 26 , Issue 1 , Pages S22 – S27)

    Not wild about cow collagen, not wild about pig collagen either! 🙂

    Comment by Katie on September 14, 2008 at 11:38 pm

  2. I have little experience with Radiesse, but have seen some bad results when it was injected into the lips in the past. Otherwise, there are so many fillers on the market, it’s hard to carry and be excellent at using all of them.
    As far as transoral injection, I wouldn’t be a fan of that. I think it would be harder to place the product in the right location using that technique, but that’s just my opinion. Thanks for the comments!

    Comment by Dr. Tony Youn on September 17, 2008 at 1:45 pm

  3. Watching E! and hey your on it!! i just stumbled upon your website when googling evolence….good site..informative and entertaining! Wish you were in TX.

    Comment by Anonymous on September 19, 2008 at 8:14 pm

  4. We have just started using Artefill as a filler and have seen a great response from the product. Have you ever used it before?

    Comment by Jeffrey Raval, MD on November 10, 2008 at 6:12 pm

  5. Dr. Raval,
    No, I haven’t used Artefill before. I have some concerns regarding permanent fillers. What happens if you or the patient are unhappy with the results?
    Thanks for reading.
    Dr. Youn

    Comment by Dr. Tony Youn on November 10, 2008 at 8:47 pm

  6. That is a very common concern with our patients, and we highly advise them on the outcomes. We have only recently started using the product and if you’d like let you know how it turns out.

    Thanks for the great content!

    Comment by Jeffrey Raval, MD on November 12, 2008 at 12:56 pm

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